Man Concerned About a New Spot On His Lip Let's Diagnose VisualDx Pigmented Lesions of the Oral Mucosa Pocket Dentistry ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Differentiating between early melanomas and melanocytic nevi: A state of the art review ScienceDirect