LEAP2: A novel regulator of food intake and body weight? Nature Reviews Gastroenterology & Hepatology Ipamorelin and CJC 1295 are almost always discussed together in research circles, and the reason comes down to receptor pharmacology. The two peptides work through entirely different but complementary mechanisms that produce a Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives Ipamorelin is a potent growth hormone releasing peptide that has some potential advantages over some of the others. Although peptides seem to be doled out like aspirin, keep in mind that these are Growth Hormone Peptides; A Comparative Review Normal Physiology of ACTH and GH Release in the Hypothalamus and Anterior Pituitary in Man Endotext NCBI Bookshelf