Compounded Methylcobalamin (Vitamin B12) Injection, 5mg mL Optimal B12 Injection Sites for Maximum Absorption and Benefits Your Health Magazine Lets do my first B12 injection together This is something Ive been nervous about for a long time, but today I finally did itand it honestly wasnt bad at all. I used the Union Medico needle guide How to Give a B12 Injection: Step By Step Instructions Subcutaneous (SC) and Intramuscular (IM) Injections Must Knows for Subcutaneous administration: Pinch skin with non dominant hand and hold syringe with dominant hand Always inject: 2 inches away from umbilicus (for abdomen) 3 inches Ivy Grove Surgery : Self administration of B12 injection